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Ro4938581 is a nootropic drug invented in 2009 by a workforce Doing work for Hoffmann-La Roche, which acts as a subtype-selective inverse agonist with the αfive subtype in the benzodiazepine binding internet site on the GABAA receptor. It has very good selectivity for your αfive subtype and didn't make convulsant or anxiogenic outcomes in animal